The Yip Lab

PUBLICATIONS

Westbye, A.B., Kuchinski, K., Yip, C.K., Beatty, J.T. The gene transfer agent RcGTA contains head spikes needed for binding to the Rhodobacter capsulatus polysaccharide cell capsule. (2015) Journal of Molecular Biology (In press)

Morris, D.H., Yip, C.K., Shi, Y., Chait, B.T., Wang, Q.J. Beclin1-VPS34 complex architecture: understanding the nuts and bolts of therapeutic targets. (2015) Frontiers in Biology 10:398-426 (Featured in Cover)

Chew, L.H., Lu, S., Liu, X., Li, F.K., Yu, A.Y., Klionsky, D.J., Dong, M.Q., Yip, C.K. Molecular interactions of the Saccharomyces cerevisiae Atg1 complex provide insights into assembly and regulator mechanisms. (2015) Autophagy 11: 891-905. (Featured in Cover)

Kerr, C.H., Wang, Q.S., Keatings, K., Khong, A., Allan, D., Yip, C.K., Foster, L.J., Jan, E. The 5′ untranslated region of a novel infectious molecular clone of the dicistrovirus cricket paralysis virus modulates infection. (2015) Journal of Virology 89: 5919-5934.

Setiaputra, D., Ross, J.D., Lu, S., Cheng, D.T., Dong, M.Q., Yip, C.K. Conformational flexibility and subunit arrangement of the modular yeast Spt-Ada-Gcn5 acetyltransferase complex. (2015) Journal of Biological Chemistry 290: 10057-10070.

Solomonson, M., Setiaputra, D., Makepeace, K.A., Lameignere, E., Petrotchenko, E.V., Conrady, D.G., Bergeron, J.R., Vuckovic, M., DiMaio, F., Borchers, C.H., Yip, C.K., Strynadka, N.C. Structure of EspB from the ESX-1 type VII secretion system and insights into its export mechanism. (2015) Structure 23:571-583.

Chan, C.S., Song, X., Qazi, S.J., Setiaputra, D., Yip, C.K., Chao, T., Turner, R.J. Unusual pairing between assistants: Interaction of the twin-arginine system-specific chaperone DmsD with the chaperonin GroEL. (2015)  Biochemical and Biophysical Research Communications 456: 841-846.

Lamour, G., Yip, C.K., Li, H., Gsponer, J. High intrinsic mechanical flexibility of mouse prion nanofibrils revealed by measurements of axial and radial young’s moduli. (2014) ACS Nano 8: 3851-3861.

Chew, L.H., Yip, C.K. Structural biology of the macroautophagy machinery. (2014) Frontiers in Biology 9: 18-34.

Mao, K., Chew, L.H., Yip, C.K., Klionsky, D.J. The role of Atg29 phosphorylation in PAS assembly. (2013) Autophagy 9: 2178-2179.

Chew, L.H., Setiaputra, D., Klionsky, D.J., Yip, C.K. Structural characterization of the Saccharomyces cerevisiae autophagy regulatory complex Atg17-Atg31-Atg29. (2013) Autophagy 9: 1467-1474.

Mao, K., Chew, L.H., Inoue, Y., Cheong, H., Nair, U., Popelka, H., Yip, C.K., Klionsky, D.J. Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. (2013) Proceedings of the National Academy of Sciences of the USA 110: E2875-E2884.

Chambers, M.G., Pyburn, T.M., Gonzalez-Rivera, C., Collier, S.E., Eli, I., Yip, C.K., Takizawa, Y., Lacy, D.B., Cover, T.L., Ohi, M.D. Structural analysis of the oligomeric states of Helicobacter pylori VacA toxin. (2013) Journal of Molecular Biology 425: 524-535.

Yip, C.K., Walz, T. Molecular structure and flexibility of the yeast coatomer as revealed by electron microscopy. (2011) Journal of Molecular Biology 408: 825-831.

Yip, C.K., Berscheminski, J., Walz, T. Molecular architecture of the TRAPPII complex and implications for vesicle tethering. (2010) Nature Structural & Molecular Biology 17: 1298-1304.

Lees, J.*, Yip, C.K.*, Walz, T., Hughson, F.M. Molecular organization of the COG vesicle tethering complex. (2010) Nature Structural & Molecular Biology 17: 1292-1297. *Authors contributed equally

Corbett, K.D., Yip, C.K., Ee, L., Walz, T., Amon, A., Harrison, S.C. The monopolin complex cross-links kinetochore compoments to regulate chromosome-microtubule attachments. (2010) Cell 142: 556-567.

Yip, C.K., Murata, K., Walz, T., Sabatini, D.M., Kang, S.A. (2010) Structure of the human mTOR Complex I and its implications for rapamycin inhibition. Molecular Cell 38: 768-774.

Ren, Y., Yip, C.K., Tripathi, A., Huie, D., Jeffrey, P.D., Walz, T., Hughson, F.M. (2009) A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1. Cell 139: 1119-1129.

Li, H., Motamedi, M.R., Yip, C.K., Wang, Z., Walz, T., Patel, D.J., Moazed, D. (2009) An alpha motif at Tas3C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Molecular Cell 34: 155-167.

Wu, W., Sinha, D., Shikov, S., Yip, C.K., Walz, T., Billings, P.C., Lear, J.D., Walsh, P.N. (2008) Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIa. Journal of Biological Chemistry 283: 18655-18664.

a place of mind, The University of British Columbia

Yip Lab
Life Sciences Institute
Rm 5340, 2350 Health Sciences Mall,
Vancouver, BC, V6T 1Z3, Canada

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